Choosing the right weed killer for St Augustine grass can protect your lawn from common broadleaf and grassy weeds. The following selections are formulated or commonly used for St Augustine and centipede grasses, offering targeted control, easy application, and compatibility with typical Southern lawns. Review each option’s strength, application area, and weed targets to make an informed choice.
| Product | Brand | Coverage | Notes |
|---|---|---|---|
| Southern Ag 006130 Atrazine St. Augustine Weed Killer | Southern Ag | 3,720 sq ft (quart) | Controls weeds in St Augustine and Centipede grasses |
| Southern Ag Atrazine St. Augustine Grass Weed Killer | Southern Ag | 1 gallon | Kills many broadleaf weeds; crabgrass suppression |
| Hi-Yield Atrazine Weed Killer | VPG | Varies by rate | For St. Augustine and Centipede grasses |
| BioAdvanced 3-in-1 Weed and Feed for Southern Lawns | BioAdvanced | Season-long protection (up to 6 months) | Weed killer and lawn fertilizer for Southern lawns |
| Southern Ag – 13503 Lawn Weed Killer with Trimec | Southern Ag | Several turf types | Combination of 3 weed killers |
Southern Ag Atrazine St. Augustine Weed Killer 32oz

Product: Southern Ag 006130 Atrazine St. Augustine Weed Killer 32oz Specialty Herbicide, Light Tan. Brand: Southern Ag. Features include coverage for 3,720 sq ft per quart and effective weed control in St. Augustine and Centipede grasses. This option is designed for homeowners seeking a focused reticle on common St. Augustine weeds with straightforward application. Consider use when broadleaf weed growth is evident and crabgrass suppression is not the primary goal.
Southern Ag Atrazine St. Augustine Grass Weed Killer

Product: Southern Ag Atrazine St. Augustine Grass Weed Killer, 1 Gallon. Brand: Southern Ag. Features include broadleaf weed control and compatibility with centipede grass, with suppression of crabgrass. This larger size is suitable for bigger lawns or seasonal maintenance programs where repeat treatments are planned.
Hi-Yield Atrazine Weed Killer

Product: Hi-Yield Atrazine Weed Killer. Brand: VPG. Features include Atrazine at 4.00% and weeds controlled or suppressed such as annual bluegrass, chickweed, and more. For use in St. Augustine and Centipede grasses. This option is a solid choice when targeting specific grassy and broadleaf weeds in warm-season lawns.
BioAdvanced 3-in-1 Weed and Feed for Southern Lawns

Product: BioAdvanced 3-in-1 Weed and Feed for Southern Lawns, Granules, 10 lb. Brand: BioAdvanced. Features include Southern lawn suitability (Bermudagrass, St. Augustinegrass, including Floratam), up to 6 months of weed prevention, and the combination of weed killing with lawn fertilization to maintain lawn health and curb weed growth.
Southern Ag – 13503 Lawn Weed Killer with Trimec

Product: Southern Ag – 13503 Lawn Weed Killer with Trimec – Herbicide – 32oz. Brand: Southern Ag. Features include use on 9 turf types, broad weed range control, and a patented combination of three proven weed killers. Ideal for homes seeking a versatile weed control product that can address multiple weed species across several warm-season grasses, including St Augustine and centipede.
Agralawn Crabgrass Killer (2, Pounds)

Product: Agralawn Crabgrass Killer (2 Pounds). Brand: Agralawn. Features include use on St. Augustine, common Bermuda, Bahia, and Centipede grasses; effective leaf absorption with root impact; designed to minimize harm to St Augustine when used as directed. A post-emergent option useful for controlling actively growing weeds.
Sunniland St.Augustine Weed & Feed Lawn Fertilizer

Product: Sunniland St.Augustine Weed & Feed Lawn Fertilizer for St. Augustine Grass 5000 sq ft. Brand: Generic. Features include easy-to-spread granules, two applications in spring and fall, and compatibility with all St. Augustine grass varieties. Combines weed control with fertilization for routine lawn maintenance.
Hi-Yield (33431) Atrazine Weed Killer RTS

Product: Hi-Yield (33431) Atrazine Weed Killer RTS (32 oz). Brand: Hi-Yield. Features include selective weed control for Henbit, Clover, Chickweed, and more; intended for use on St. Augustine and Centipedegrass; treats up to 3,720 sq. feet of lawn per bottle. Useful for common cool-season and some warm-season weeds that invade St. Augustine lawns.
Buying Guide: Key Purchase Considerations
- Target weeds: Identify the weed species you’re dealing with (crabgrass, dandelion, clover, chickweed) and choose products listed as effective against those weeds.
- Grass compatibility: Ensure the product is labeled for St. Augustine and related grasses like centipede or Floratam variants to minimize turf damage.
- Active ingredient: Atrazine-based products are common for St. Augustine lawns; consider the environmental impact and regulatory guidelines in your area.
- Application rate and coverage: Check square footage coverage per bottle to plan applications across your lawn and avoid under- or over-application.
- Formulation and use: Granular might require watering in; liquid concentrates often allow precise mixing. Some products offer combined weed control and fertilization for ongoing lawn health.
- Seasonality: Some products provide long-term prevention (up to 6 months) while others require more frequent re-application.
- Safety and handling: Follow label directions, wear protective gear as recommended, and keep children/pets away during application.
- Environmental considerations: Be mindful of runoff pathways and proximity to non-target plants or waterways.