When dealing with household pests, choosing an effective ant and roach killer is essential for a safer, cleaner home. This guide compares select products that target ants, roaches, and related insects, providing objective insights to help American households decide what to buy. Each option covers indoor use, residual protection, and practical application notes to fit different spaces.
Summary of selected products:
| Product | Brand | Use Type | Key Benefit |
|---|---|---|---|
| Raid Ant & Roach Killer 26 | Raid | Spray (fragrance-free) | Immediate kill with up to 13 weeks residual |
| STEM Kills Ants, Roaches And Flies | STEM | Plant-based spray | Botanical active ingredient, safe when used as directed |
| Ortho Orthene Ant and Roach Killer | Ortho | Insect killer dust | Long-lasting control up to 8 months |
| Ortho Home Defense Insect Killer | Ortho | Spray for indoor and perimeter | Broad indoor & perimeter protection up to 12 months |
| TERRO Ant & Roach Bait | Terro | Bait stations | Colony-wide baiting to reduce populations |
Note: This article reviews products that target both ants and cockroaches, along with related pests. Always follow label directions, use protective equipment as needed, and test a small area before broad application.
Raid Ant & Roach Killer 26 (Fragrance Free) — 17.5 Oz

Raid Ant & Roach Killer provides broad-spectrum contact kill for a wide range of crawling pests, including cockroaches, waterbugs, ants, and others. The product offers residual insecticide protection for up to 13 weeks, helping to suppress re-infestation after initial treatment. It is fragrance-free, making it suitable for sensitive spaces like kitchens and pantries. Use on infested surfaces and in cracks or entry points to establish a temporary barrier against pests.
STEM Kills Ants, Roaches And Flies

This plant-based spray uses a botanical active ingredient to kill ants, roaches, and flies. It is designed for indoor and outdoor use and emphasizes a safer profile for households with people and pets when used as directed. The formula is fragrance-light with no added dye, designed to reduce harsh chemical odors while delivering fast knockdown and residual control against common urban pests.
Ortho Orthene Ant And Roach Killer (Dust)

Ortho Orthene Ant & Roach Killer is a ready-to-use dust that provides extended control, with effectiveness lasting up to eight months. It targets a broad range of pests including ants, roaches, fleas, ticks, spiders, and scorpions. Best applied into cracks, crevices, and other hideouts, and can also be used outdoors as a perimeter or plant treatment to protect ornamentals and vegetables from pests.
Ortho Home Defense Insect Killer For Indoor And Perimeter2

Ortho Home Defense offers an integrated approach for indoors and perimeters, providing a long-lasting barrier against common home-invading insects, including ants, roaches, and spiders. The product is designed for kitchens, bathrooms, and outdoor perimeter use, creating a protective edge around doors, windows, and foundation lines. With a 12-month protection window on non-porous surfaces, it helps reduce recurring pest activity when used as directed.
TERRO Ant & Roach Bait — 4 Bait Stations

Terro’s bait stations attract and kill ants and roaches by delivering a protein-based paste bait that workers share with the colony, targeting both visible and hidden pests. The kit includes four bait stations designed for indoor use in kitchens, pantries, and other high-traffic areas. By combining attraction with delayed-action poisoning, Terro aims to reduce entire colonies over time and limit re-infestation.
Raid Ant & Roach Killer Spray For Listed Bugs

Raid Ant & Roach Killer Spray provides rapid knockdown on contact with a residual effect that lasts up to 13 weeks for roaches and carpenter ants. The lemon-scented spray is designed for direct application on infested surfaces and can be used to suppress ongoing pest activity in kitchens, bathrooms, basements, and other areas where ants and roaches enter. It combines ease of use with extended protection for treated sites.
Ortho Orthene Fire Ant Killer

Ortho Orthene Fire Ant Killer targets fire ant mounds directly, including queen destruction, with rapid action starting within an hour. The product is designed for outdoor use and protects lawns, ornamentals, and gardens from fire ant colonies by treating up to 162 mounds. Outdoor application helps reduce reinfestation around homes and landscaped areas.
Buying Guide: Key Purchase Considerations
When selecting an ant and roach killer, consider the following factors:
- Active ingredients and pest targets: Confirm whether the product targets ants, roaches, or both, and whether it covers additional pests like silverfish or crickets.
- Application method: Sprays, dusts, and bait stations suit different spaces. Sprays are good for quick knockdown; dusts help in cracks; baits address colonies over time.
- Indoor vs. outdoor use: Some formulas are better for indoor living areas, while others are designed for perimeter treatments or outdoor morthd controls.
- Residual protection: Look for products that offer lasting protection to reduce re-infestation, especially in kitchens, bathrooms, and entry points.
- Safety and fragrance: Fragrance-free or low-odor formulas are preferable in homes with sensitivities; consider plant-based or low-toxicity options for households with pets and children.
- Surface compatibility: Check whether the product is safe on non-porous surfaces like tile, glass, or stainless steel, and avoid porous materials unless specified.
- Colony vs. surface control: Bait stations and protein-based baits target colonies, while sprays and dusts provide immediate surface knockdown.
Practical usage tips:
- Read and follow label directions for dosing, safety, and storage.
- Apply treatments to known entry points, cracks, and trails for better effectiveness.
- Use bait stations in quiet areas away from children and pets if households are present.
- Combine indoor treatments with exterior perimeter care for comprehensive protection.